Apply TMM Harmonization with frozen parameters to Precision Object

Trimmed Mean of M-values (TMM) normalization for miRNA-Seq data using the edgeR package. For more information, visit the documentation on the edgeR package website.

Usage

harmon.TMM.frozen(object)

Arguments

object

A precision object containing raw data. Harmonization is applied to the slots raw.train.data, raw.test1.data, and raw.test2.data (if applicable), each containing a list with data and label elements.

Value

A precision object with TMM harmonization results added to the slots harmon.train.data, harmon.test1.data, and harmon.test2.data (if applicable).

Details

This function applies TMM harmonization using frozen parameters to the raw data contained in a precision object. The harmonization results are added to the corresponding slots in the object for each dataset ("train", "test1", "test2") if they exist.